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2022 Mercedes-Benz CLS-Class CLS 450

Specifications, live market data, colors, and factory features.

25 for sale right now

$34,774 – $48,997

View Listings

Specifications

362
Horsepower
369
lb-ft Torque
25
MPG Combined
5
Seats
$73k
Base MSRP

Performance

Engine
3.0L V-Shaped M256
Horsepower
362 hp
Torque
369 lb-ft
Transmission
9-Speed Automatic
Drivetrain
AWD

Fuel & Efficiency

Fuel
Gasoline
MPG City
22 mpg
MPG Highway
30 mpg
MPG Combined
25 mpg
Fuel Tank
21.1 gal

Dimensions

Length
198.8″
Width
73.8″
Height
56.6″
Wheelbase
115.7″
Curb Weight
4,255 lbs
Cargo Volume
11.9 cu ft

Body & Practicality

Body Style
Coupe
Doors
4
Seating
5
Base MSRP
$72,950

Colors

Factory colors on 2022 Mercedes-Benz CLS-Class CLS 450s for sale now.

Exterior

  • MANUFAKTUR Diamond White Bright(white)3
  • Black3
  • Polar White(white)3
  • Gray2
  • White2
  • Graphite Gray Metallic(gray)2
  • Selenite Grey Metallic(gray)1
  • Obsidian Black Metallic(black)1
  • MANUFAKTUR Selenite Grey Magno(gray)1
  • Silver Metallic(silver)1

Interior

  • Black7
  • Classic Red/Black(black)3
  • Black Leather(black)2
  • Macchiato Beige/Magma Gray(gray)1
  • Yacht Blue/Black(black)1
  • Sienna Brown/Black(black)1
  • Brown1
  • Black Nappa Leather(black)1
  • Macchiato & Magma Grey(gray)1
  • Beige(brown)1

Live Market Data

Computed from active 2022 Mercedes-Benz CLS-Class CLS 450 listings nationwide, updated continuously.

For sale now25
Median price$41,990
Average price$42,254
Price range$34,774 – $48,997
Median vs. MSRP−$30,960
Avg. days on market86
Avg. mileage35,918 mi
New / Used0 / 25

Price Distribution

median $42k$36k$49k

Price vs. Mileage

0 mi64k mi$49k$36k

Latest CLS 450 Listings

The newest 2022 Mercedes-Benz CLS-Class CLS 450s on the market.

View all 25 →
View Used 2022 Mercedes-Benz CLS-Class listing

Used 2022 Mercedes-Benz CLS-Class

CLS 450

$41,990

42,672 mi

Est. $612/mo*

4 days at this dealer
WhiteBlack

Abramovich Motors

Murrieta, CA
View Used 2022 Mercedes-Benz CLS-Class listing

Used 2022 Mercedes-Benz CLS-Class

CLS 450

$42,243

31,401 mi

Est. $615/mo*

7 days at this dealer
GrayGray

Porsche South Bay

Hawthorne, CA
View Used 2022 Mercedes-Benz CLS-Class listing

Used 2022 Mercedes-Benz CLS-Class

CLS 450

$48,015

24,953 mi

Est. $698/mo*

11 days at this dealer
BlackBlack

Fletcher Jones Motorcars

Newport Beach, CA
View Used 2022 Mercedes-Benz CLS-Class listing

Used 2022 Mercedes-Benz CLS-Class

CLS 450

$48,584

21,291 mi

Est. $706/mo*

13 days at this dealer
BlackGray

Mercedes-Benz of Hilton Head

Bluffton, SC
View Used 2022 Mercedes-Benz CLS-Class listing

Used 2022 Mercedes-Benz CLS-Class

CLS 450

$45,049

32,953 mi

Est. $655/mo*

18 days at this dealer
BlackBlack

West End Lincoln

Saint Louis Park, MN
View Used 2022 Mercedes-Benz CLS-Class listing

Used 2022 Mercedes-Benz CLS-Class

CLS 450

$37,995

43,415 mi

Est. $555/mo*

48 days at this dealer
Polar WhiteBlack

Mercedes-Benz of Sacramento

Sacramento, CA
View Used 2022 Mercedes-Benz CLS-Class listing

Used 2022 Mercedes-Benz CLS-Class

CLS 450

$47,069

44,356 mi

Est. $684/mo*

51 days at this dealer
GrayRed

Auto Race

Sunnyvale, CA
View Certified 2022 Mercedes-Benz CLS-Class listing

Certified 2022 Mercedes-Benz CLS-Class

CLS 450

$44,448

24,657 mi

Est. $647/mo*

75 days at this dealer
Polar WhiteBlack Leather

Mercedes-Benz of Greenwich

Greenwich, CT

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The median 2022 Mercedes-Benz CLS-Class CLS 450 lists for $41,990 today.

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Factory Features

Standard equipment from the window sticker, reviewed for accuracy.

Comfort & Convenience

  • KEYLESS-START
  • KEYLESS-GO Comfort Package (standard): KEYLESS-GO, HANDS-FREE ACCESS, and electronic trunk closer
  • Remote start capability
  • Keyless entry
  • Power-adjustable front seats with memory
  • Heated front seats
  • USB-C ports
  • Power mirrors
  • Rain-sensing wipers

Driver Assistance

  • Active Brake Assist
  • Blind Spot Assist
  • ATTENTION ASSIST
  • Adaptive Highbeam Assist
  • Parking Damage Detection System
  • Car-to-X Communication
  • Cruise control (basic; adaptive DISTRONIC requires optional Driver Assistance Package)
  • Rearview camera (federal requirement)

Entertainment

  • MBUX (Mercedes-Benz User Experience) infotainment system
  • MBUX navigation with voice control
  • AI natural language understanding with keyword activation (“Hey Mercedes”)
  • 12.3-inch center touchscreen display
  • 12.3-inch digital instrument cluster
  • COMAND Navigation with map updates and live traffic for 3 years
  • Smartphone Integration with Apple CarPlay
  • Smartphone Integration with Android Auto
  • Bluetooth connectivity
  • Steering-wheel Touch Control interface
  • Standard Mercedes-Benz audio system (Burmester is optional)

Exterior

  • AMG Line / AMG body styling (standard for 2022)
  • AMG-specific front bumper with A-wing, air intakes, and silver-chrome front splitter
  • AMG side sill trim
  • Rear bumper with black diffuser-look insert and silver-chrome trim strip
  • New radiator grille with three-dimensional Mercedes-Benz star pattern
  • 19-inch alloy wheels (standard; 5-twin-spoke or multi-spoke designs)
  • LED headlamps
  • LED Intelligent Light System with Adaptive Highbeam Assist (standard for 2022)
  • LED taillamps
  • LED daytime running lamps
  • Frameless doors
  • Power sunroof
  • Rain-sensing windshield wipers
  • Power-folding exterior mirrors
  • Hands-free Access power trunk operation

Interior

  • Leather upholstery
  • 5-passenger seating
  • Heated front seats with power adjustment, memory, and lumbar support
  • Multifunction Nappa leather steering wheel with capacitive Touch Control buttons and silver-chrome paddle shifters
  • 64-color ambient lighting
  • Illuminated turbine-design air vents
  • 12.3-inch digital instrument cluster
  • 12.3-inch central touchscreen display (widescreen dual-display layout)
  • Dual-zone automatic climate control
  • Power windows
  • Auto-dimming rearview mirror

Mechanical & Performance

  • 3.0L inline-6 turbocharged engine with 48-volt mild-hybrid system (EQ Boost / ISG)
  • 362 horsepower @ 5,500–6,100 rpm
  • 369 lb-ft of torque @ 1,600–4,000 rpm
  • Integrated Starter-Generator electric assist: up to +21 hp and +184 lb-ft
  • Energy recuperation and engine-off coasting/sailing capability
  • Electric refrigerant compressor for climate system
  • 9G-TRONIC 9-speed automatic transmission
  • 4MATIC all-wheel drive
  • DYNAMIC SELECT drive modes
  • ECO start/stop system
  • Electronically limited top speed of 130 mph
  • 0–60 mph in approximately 4.5–4.7 seconds (manufacturer estimate)

Safety & Security

  • PRE-SAFE anticipatory occupant protection system
  • PRE-SAFE Sound
  • Active Brake Assist (forward collision warning with automatic emergency braking; can respond to stationary vehicles and crossing pedestrians at city speeds)
  • ATTENTION ASSIST driver drowsiness/attention monitoring
  • Blind Spot Assist
  • Parking Damage Detection System
  • Car-to-X Communication
  • Antilock braking system (ABS)
  • Brake Assist / emergency brake assist
  • Electronic stability control
  • Traction control
  • Tire pressure monitoring system
  • Dual-stage front airbags
  • Front side-impact airbags
  • Side curtain/window airbags
  • Driver knee airbag
  • Child seat anchors (LATCH) and child safety door locks
  • Antitheft alarm system
  • Engine immobilizer

Warranty

  • 4-year / 50,000-mile new vehicle limited warranty (whichever comes first)
  • 4-year / 50,000-mile roadside assistance (Mercedes-Benz USA coverage period)