2022 Mercedes-Benz CLS-Class CLS 450
Specifications, live market data, colors, and factory features.
29 for sale right now
$35,447 – $51,882
Specifications
Performance
- Engine
- 3.0L V-Shaped M256
- Horsepower
- 362 hp
- Torque
- 369 lb-ft
- Transmission
- 9-Speed Automatic
- Drivetrain
- AWD
Fuel & Efficiency
- Fuel
- Gasoline
- MPG City
- 22 mpg
- MPG Highway
- 30 mpg
- MPG Combined
- 25 mpg
- Fuel Tank
- 21.1 gal
Dimensions
- Length
- 198.8″
- Width
- 73.8″
- Height
- 56.6″
- Wheelbase
- 115.7″
- Curb Weight
- 4,255 lbs
- Cargo Volume
- 11.9 cu ft
Body & Practicality
- Body Style
- Coupe
- Doors
- 4
- Seating
- 5
- Base MSRP
- $72,950
Colors
Factory colors on 2022 Mercedes-Benz CLS-Class CLS 450s for sale now.
Exterior
- Black5
- Polar White(white)3
- Gray3
- Graphite Gray Metallic(gray)2
- White2
- Silver1
- MANUFAKTUR Mystic Blue(blue)1
- Silver Metallic(silver)1
- WHITE1
- Graphite Grey Metallic(black)1
Interior
- Black6
- Black Leather(black)3
- Classic Red/Black(red)2
- Sienna Brown/Black(brown)2
- Brown1
- Deep White/Black(white)1
- Macchiato & Magma Grey(brown)1
- Beige(red)1
- Macchiato/Magma Grey(red)1
- Sienna Brown/Black Leather(brown)1
Live Market Data
Computed from active 2022 Mercedes-Benz CLS-Class CLS 450 listings nationwide, updated continuously.
Price Distribution
Price vs. Mileage
Latest CLS 450 Listings
The newest 2022 Mercedes-Benz CLS-Class CLS 450s on the market.

Used 2022 Mercedes-Benz CLS-Class
$49,069
Est. $713/mo*
AUTO RACE

Used 2022 Mercedes-Benz CLS-Class
$50,455
Est. $732/mo*
Mercedes-Benz of Hanover

Certified 2022 Mercedes-Benz CLS-Class
$49,386
Est. $717/mo*
Ricart Ford

Used 2022 Mercedes-Benz CLS-Class
$44,035
Est. $641/mo*
Autobahn USA Westborough

Used 2022 Mercedes-Benz CLS-Class
$49,649
Est. $721/mo*
Mercedes-Benz of Greenwich

Used 2022 Mercedes-Benz CLS-Class
$51,882
Est. $753/mo*
Mercedes-Benz of Willoughby

Used 2022 Mercedes-Benz CLS-Class
$47,365
Est. $688/mo*
Cox & Co. Motorcars

Used 2022 Mercedes-Benz CLS-Class
$46,269
Est. $673/mo*
Audi West Palm Beach
What's Yours
Worth?
The median 2022 Mercedes-Benz CLS-Class CLS 450 lists for $42,994 today.
Check My Car's ValuePowered by live market data
Sell Your
Mercedes-Benz CLS-Class CLS 450
Get a competitive offer for your CLS-Class— we'll come pick it up.
StartGet your offer · Schedule pickup · Get paid on the spot
Save on
Auto Insurance
Get a Quote Now!Powered by TheZebra
Factory Features
Standard equipment from the window sticker, reviewed for accuracy.
Comfort & Convenience
- KEYLESS-START
- KEYLESS-GO Comfort Package (standard): KEYLESS-GO, HANDS-FREE ACCESS, and electronic trunk closer
- Remote start capability
- Keyless entry
- Power-adjustable front seats with memory
- Heated front seats
- USB-C ports
- Power mirrors
- Rain-sensing wipers
Driver Assistance
- Active Brake Assist
- Blind Spot Assist
- ATTENTION ASSIST
- Adaptive Highbeam Assist
- Parking Damage Detection System
- Car-to-X Communication
- Cruise control (basic; adaptive DISTRONIC requires optional Driver Assistance Package)
- Rearview camera (federal requirement)
Entertainment
- MBUX (Mercedes-Benz User Experience) infotainment system
- MBUX navigation with voice control
- AI natural language understanding with keyword activation (“Hey Mercedes”)
- 12.3-inch center touchscreen display
- 12.3-inch digital instrument cluster
- COMAND Navigation with map updates and live traffic for 3 years
- Smartphone Integration with Apple CarPlay
- Smartphone Integration with Android Auto
- Bluetooth connectivity
- Steering-wheel Touch Control interface
- Standard Mercedes-Benz audio system (Burmester is optional)
Exterior
- AMG Line / AMG body styling (standard for 2022)
- AMG-specific front bumper with A-wing, air intakes, and silver-chrome front splitter
- AMG side sill trim
- Rear bumper with black diffuser-look insert and silver-chrome trim strip
- New radiator grille with three-dimensional Mercedes-Benz star pattern
- 19-inch alloy wheels (standard; 5-twin-spoke or multi-spoke designs)
- LED headlamps
- LED Intelligent Light System with Adaptive Highbeam Assist (standard for 2022)
- LED taillamps
- LED daytime running lamps
- Frameless doors
- Power sunroof
- Rain-sensing windshield wipers
- Power-folding exterior mirrors
- Hands-free Access power trunk operation
Interior
- Leather upholstery
- 5-passenger seating
- Heated front seats with power adjustment, memory, and lumbar support
- Multifunction Nappa leather steering wheel with capacitive Touch Control buttons and silver-chrome paddle shifters
- 64-color ambient lighting
- Illuminated turbine-design air vents
- 12.3-inch digital instrument cluster
- 12.3-inch central touchscreen display (widescreen dual-display layout)
- Dual-zone automatic climate control
- Power windows
- Auto-dimming rearview mirror
Mechanical & Performance
- 3.0L inline-6 turbocharged engine with 48-volt mild-hybrid system (EQ Boost / ISG)
- 362 horsepower @ 5,500–6,100 rpm
- 369 lb-ft of torque @ 1,600–4,000 rpm
- Integrated Starter-Generator electric assist: up to +21 hp and +184 lb-ft
- Energy recuperation and engine-off coasting/sailing capability
- Electric refrigerant compressor for climate system
- 9G-TRONIC 9-speed automatic transmission
- 4MATIC all-wheel drive
- DYNAMIC SELECT drive modes
- ECO start/stop system
- Electronically limited top speed of 130 mph
- 0–60 mph in approximately 4.5–4.7 seconds (manufacturer estimate)
Safety & Security
- PRE-SAFE anticipatory occupant protection system
- PRE-SAFE Sound
- Active Brake Assist (forward collision warning with automatic emergency braking; can respond to stationary vehicles and crossing pedestrians at city speeds)
- ATTENTION ASSIST driver drowsiness/attention monitoring
- Blind Spot Assist
- Parking Damage Detection System
- Car-to-X Communication
- Antilock braking system (ABS)
- Brake Assist / emergency brake assist
- Electronic stability control
- Traction control
- Tire pressure monitoring system
- Dual-stage front airbags
- Front side-impact airbags
- Side curtain/window airbags
- Driver knee airbag
- Child seat anchors (LATCH) and child safety door locks
- Antitheft alarm system
- Engine immobilizer
Warranty
- 4-year / 50,000-mile new vehicle limited warranty (whichever comes first)
- 4-year / 50,000-mile roadside assistance (Mercedes-Benz USA coverage period)