2021 Mercedes-Benz E-Class E 350
Specifications, live market data, colors, and factory features.
118 for sale right now
$20,946 – $51,982
Specifications
Performance
- Engine
- 2.0L inline 4 M264
- Horsepower
- 255 hp
- Torque
- 273 lb-ft
- Transmission
- 9-Speed Automatic
- Drivetrain
- RWD
Fuel & Efficiency
- Fuel
- Gasoline
- MPG City
- 22 mpg
- MPG Highway
- 31 mpg
- MPG Combined
- 25 mpg
- Fuel Tank
- 17.4 gal
Dimensions
- Length
- 194.3″
- Width
- 73.7″
- Height
- 57.8″
- Wheelbase
- 115.7″
- Curb Weight
- 3,781 lbs
- Cargo Volume
- 13.1 cu ft
Body & Practicality
- Body Style
- Sedan
- Doors
- 4
- Seating
- 5
- Base MSRP
- $54,250
Colors
Factory colors on 2021 Mercedes-Benz E-Class E 350s for sale now.
Exterior
- Black20
- Polar White(white)14
- White12
- Silver8
- Cirrus Silver Metallic(silver)4
- Lunar Blue Metallic(blue)4
- Selenite Grey Metallic(gray)3
- Hightech Silver(silver)2
- Graphite Gray(gray)2
- Graphite Grey Metallic(gray)2
Interior
- Black39
- Black MB Tex(black)7
- Artico Almond Beige(brown)5
- Macchiato Beige(brown)4
- Macchiato Beige/Black(brown)4
- Beige(brown)3
- Gray2
- Artico Alpaca Grey(brown)2
- Nut Brown/Black(brown)1
- Deep White/Black(white)1
Live Market Data
Computed from active 2021 Mercedes-Benz E-Class E 350 listings nationwide, updated continuously.
Price Distribution
Price vs. Mileage
Latest E 350 Listings
The newest 2021 Mercedes-Benz E-Class E 350s on the market.

Used 2021 Mercedes-Benz E-Class
$32,950
Est. $483/mo*
Executive Auto Center

Used 2021 Mercedes-Benz E-Class
$28,319
Est. $417/mo*
Baha Auto

Used 2021 Mercedes-Benz E-Class
$29,000
Est. $427/mo*
Mercedes-Benz of Midlothian

Used 2021 Mercedes-Benz E-Class
$25,985
Est. $384/mo*
Ie Motors Direct

Used 2021 Mercedes-Benz E-Class
$31,040
Est. $456/mo*
AutoLenders Palm Harbor

Used 2021 Mercedes-Benz E-Class
$34,993
Est. $512/mo*
Mercedes-Benz of Raleigh

Used 2021 Mercedes-Benz E-Class
$24,579
Est. $364/mo*
W.I. Simonson Mercedes-Benz

Used 2021 Mercedes-Benz E-Class
$30,098
Est. $442/mo*
Grand Motorcars
What's Yours
Worth?
The median 2021 Mercedes-Benz E-Class E 350 lists for $30,382 today.
Check My Car's ValuePowered by live market data
Sell Your
Mercedes-Benz E-Class E 350
Get a competitive offer for your E-Class— we'll come pick it up.
StartGet your offer · Schedule pickup · Get paid on the spot
Save on
Auto Insurance
Get a Quote Now!Powered by TheZebra
Factory Features
Standard equipment from the window sticker, reviewed for accuracy.
Comfort & Convenience
- KEYLESS-START
- KEYLESS-GO (proximity keyless entry)
- Remote engine start
- Dual-zone automatic climate control
- Heated front seats
- Power front seats with driver and passenger memory
- Power tilt/sliding glass sunroof
- Integrated garage door opener (HomeLink)
- Rain-sensing windshield wipers
- Heated power-folding exterior mirrors
- Power windows
- Cruise control
Driver Assistance
- Active Brake Assist (pre-collision warning and automatic emergency braking with pedestrian detection)
- ATTENTION ASSIST (driver attention monitoring)
- Blind Spot Assist
- Crosswind Assist
- Parking Damage Detector
- Car-to-X Communication
- Cruise control
- Rearview camera
Entertainment
- Mercedes-Benz User Experience (MBUX) infotainment system with navigation
- Natural-language voice control with keyword activation (“Hey Mercedes”)
- 12.3-inch digital instrument cluster and 12.3-inch touchscreen multimedia display
- Center-console touchpad controller
- Smartphone Integration with Apple CarPlay and Android Auto
- Bluetooth hands-free phone and audio streaming
- HD Radio
- FrontBass audio system
- USB ports
Exterior
- AMG body styling
- LED headlamps
- LED taillamps
- Power tilt/sliding glass sunroof
- 18-inch alloy wheels
- Heated power-folding exterior mirrors
- Rain-sensing windshield wipers
- Privacy glass
- Power remote trunk/lid release
Interior
- 12.3-inch digital instrument cluster
- 12.3-inch touchscreen multimedia display
- 64-color ambient lighting
- MB-Tex synthetic leather upholstery
- Heated power-adjustable front seats
- Memory Package (driver and front passenger seats)
- Multifunction steering wheel with Touch Control buttons, Nappa leather wrap, and galvanized shift paddles
- Power tilt and telescoping steering column
- Dual-zone automatic climate control
- 40/20/40-split folding rear seatbacks
- Storage Package
- Power windows with one-touch express up/down
- Rear window defroster
- Cup holders
Mechanical & Performance
- 2.0L inline-4 turbocharged engine (aluminum-alloy, DOHC, 4 valves per cylinder)
- 255 horsepower @ 5,800–6,100 rpm
- 273 lb-ft of torque @ 1,800–4,000 rpm
- 9G-TRONIC 9-speed automatic transmission
- Rear-wheel drive (base E 350 Sedan)
- ECO Start/Stop system
- DYNAMIC SELECT drive-mode selector
- Independent multi-link front and rear suspension with coil springs, single-tube shock absorbers, and tubular torsion bars
- Speed-sensitive electromechanical rack-and-pinion power steering
- 4-wheel disc brakes with ABS and Brake Assist
- Electronic Stability Program (ESP) with traction control
- Hill-Start Assist
- Crosswind Assist
- 18 x 8.0-inch cast alloy wheels with 245/45 R18 all-season run-flat tires
- Electronically limited top speed of 130 mph
- 0–60 mph in 6.1 seconds (manufacturer estimate)
- 17.4-gallon fuel tank
- Premium unleaded fuel recommended
- EPA-estimated fuel economy 22 city / 31 highway / 25 combined mpg (RWD)
Safety & Security
- Active Brake Assist
- PRE-SAFE and PRE-SAFE Sound
- ATTENTION ASSIST
- Blind Spot Assist
- Crosswind Assist
- Car-to-X Communication
- Parking Damage Detector
- Rearview camera
- Anti-lock braking system (ABS) with Brake Assist
- Electronic Stability Program (ESP) and traction control
- LATCH child-seat anchors
- Child safety door locks
- Anti-theft alarm system
Warranty
- New Vehicle Limited Warranty: 4 years / 50,000 miles
- Powertrain Limited Warranty: 4 years / 50,000 miles
- Corrosion Warranty: 4 years / 50,000 miles
- Mercedes-Benz Roadside Assistance: 4 years / 50,000 miles