2022 Mercedes-Benz E-Class E 350
Specifications, live market data, colors, and factory features.
155 for sale right now
$22,219 – $58,982
Specifications
Performance
- Engine
- 2.0L inline 4 M274
- Horsepower
- 255 hp
- Torque
- 273 lb-ft
- Transmission
- 9-Speed Automatic
- Drivetrain
- RWD
Fuel & Efficiency
- Fuel
- Gasoline
- MPG City
- 23 mpg
- MPG Highway
- 31 mpg
- MPG Combined
- 26 mpg
- Fuel Tank
- 17.4 gal
Dimensions
- Length
- 194.3″
- Width
- 73.7″
- Height
- 57.8″
- Wheelbase
- 115.7″
- Curb Weight
- 3,781 lbs
- Cargo Volume
- 13.1 cu ft
Body & Practicality
- Body Style
- Sedan
- Doors
- 4
- Seating
- 5
- Base MSRP
- $54,950
Colors
Factory colors on 2022 Mercedes-Benz E-Class E 350s for sale now.
Exterior
- Black36
- Polar White(white)23
- Nautical Blue Metallic(blue)8
- White8
- Graphite Gray Metallic(gray)7
- Cirrus Silver Metallic(silver)7
- MANUFAKTUR Diamond White(white)5
- Silver4
- Gray3
- Selenite Grey Metallic(gray)2
Interior
- Black46
- Black MB-Tex(black)11
- Macchiato Beige/Black(brown)10
- Macchiato Beige(black)9
- Macchiato Beige/Black MB-Tex(brown)5
- Nut Brown/Black(brown)4
- Artico Almond Beige(brown)3
- Black MB Tex(black)3
- Macchiato Beige Black(black)2
- Neva Gray/Magma Gray(red)2
Live Market Data
Computed from active 2022 Mercedes-Benz E-Class E 350 listings nationwide, updated continuously.
Price Distribution
Price vs. Mileage
Latest E 350 Listings
The newest 2022 Mercedes-Benz E-Class E 350s on the market.

Used 2022 Mercedes-Benz E-Class
$34,593
Est. $506/mo*
Adams Auto Sale Inc.

Used 2022 Mercedes-Benz E-Class
$41,469
Est. $604/mo*
Mercedes-Benz of Covington

Used 2022 Mercedes-Benz E-Class
$40,663
Est. $593/mo*
Mercedes-Benz of Bonita Springs

Used 2022 Mercedes-Benz E-Class
$35,071
Est. $513/mo*
Mercedes-Benz of Oakland

Used 2022 Mercedes-Benz E-Class
$37,264
Est. $544/mo*
Mercedes-Benz Grapevine

Used 2022 Mercedes-Benz E-Class
$38,199
Est. $558/mo*
Mike Erdman Toyota

Used 2022 Mercedes-Benz E-Class
$31,866
Est. $467/mo*
Toyota of Cool Springs

Used 2022 Mercedes-Benz E-Class
$35,125
Est. $514/mo*
Mercedes-Benz of Austin
What's Yours
Worth?
The median 2022 Mercedes-Benz E-Class E 350 lists for $34,799 today.
Check My Car's ValuePowered by live market data
Sell Your
Mercedes-Benz E-Class E 350
Get a competitive offer for your E-Class— we'll come pick it up.
StartGet your offer · Schedule pickup · Get paid on the spot
Save on
Auto Insurance
Get a Quote Now!Powered by TheZebra
Factory Features
Standard equipment from the window sticker, reviewed for accuracy.
Comfort & Convenience
- KEYLESS-START® push-button ignition
- KEYLESS-GO® (proximity keyless entry)
- Dual-zone automatic climate control with residual-heat recirculation and air filtration
- Remote keyless entry with panic button and illuminated entry
- Smart-device remote engine start
- HomeLink® universal garage-door opener
- Three 12V power outlets
- Illuminated locking glovebox (cooled)
- Front and rear map lights; cargo-area light
- Valet function
Driver Assistance
- Active Brake Assist (forward collision warning with autonomous emergency braking)
- Blind Spot Assist
- ATTENTION ASSIST® driver-attention monitoring
- Adaptive Highbeam Assist
- Parking Damage Detector
- Car-to-X Communication
- Rearview (backup) camera
- Cruise control with steering-wheel controls
Entertainment
- MBUX infotainment system with navigation and “Hey Mercedes” natural-language voice control
- 12.3" central touchscreen multimedia display
- Center touchpad controller
- Apple CarPlay® and Android Auto® smartphone integration
- Bluetooth® hands-free calling and audio streaming
- AM/FM/HD Radio with 8-speaker FrontBass audio system
- USB connectivity / external memory support
- 4G-LTE mobile hotspot internet access
- Real-time traffic display
- Two front LCD monitors (instrument cluster + center display)
Exterior
- AMG body styling
- LED headlamps and taillamps
- Adaptive Highbeam Assist (standard for MY2022)
- LED daytime running lights
- Auto on/off headlamps with delay-off
- Power heated side mirrors with driver auto-dimming, power folding, and integrated turn signals
- Rain-sensing variable intermittent windshield wipers
- Power sliding and tilting glass sunroof with sunshade (standard single-panel; panorama roof optional)
- Chrome grille and door handles
- Body-colored bumpers; rear bumper with chrome insert
- Aluminum window trim
- Rear fog lamp(s)
- Power trunk release
Interior
- MB-Tex (synthetic leather) upholstery
- Heated 14-way power front seats with 4-way power lumbar support
- Memory Package for driver and front passenger (seats, outside mirrors, steering column, and head restraints)
- 40/20/40-split folding rear bench seat
- Front and rear center armrests (rear with storage)
- 64-color ambient lighting
- 12.3" digital instrument cluster
- Power tilt/telescoping leather-wrapped multifunction steering wheel with Touch Control buttons and galvanized shift paddles
- Auto-dimming rearview mirror
- Illuminated dual visor vanity mirrors
- Genuine wood / metal-look interior trim accents
- Power windows with one-touch up/down (front and rear)
- Power door locks with autolock
- Carpeted floor mats
- Storage Package
- Power anti-whiplash front head restraints and power-adjustable rear head restraints
Mechanical & Performance
- 2.0L turbocharged inline-4 engine (255 hp @ 5,800 rpm; 273 lb-ft @ 1,800–4,000 rpm)
- 9G-TRONIC 9-speed automatic transmission with paddle shifters
- Rear-wheel drive (E 350 base; 4MATIC optional)
- DYNAMIC SELECT drive modes
- Multi-link front and rear suspension with coil springs
- Electric power-assisted speed-sensing rack-and-pinion steering
- 4-wheel disc brakes with ABS, Brake Assist, and Electronic Stability Program (ESP)
- Hill-start assist / Hill Hold Control
- Electric parking brake
- Engine auto stop-start
- 18" alloy wheels with 245/45R18 all-season run-flat (extended mobility) tires
- Electronically limited top speed (130 mph)
Safety & Security
- PRE-SAFE® anticipatory safety system
- PRE-SAFE® Sound
- Dual-stage front airbags; front side airbags; side curtain airbags; driver knee airbag
- Airbag occupancy sensor
- Electronic Stability Program (ESP) with Crosswind Assist
- Traction control with brake-actuated torque vectoring
- Tire-pressure monitoring system (tire-specific)
- Rear child-safety locks and LATCH anchors
- Outboard seat belts with pretensioners and height adjusters; rear center 3-point belt
- Perimeter alarm and engine immobilizer
- Mercedes me connect SOS / emergency call capability
- First-aid kit
Warranty
- 4 years / 50,000 miles new-vehicle limited (basic) warranty
- 4 years / 50,000 miles powertrain warranty
- 4 years / 50,000 miles corrosion warranty
- 4 years / 50,000 miles roadside assistance