2021 Mercedes-Benz S-Class S 580
Specifications, live market data, colors, and factory features.
133 for sale right now
$44,894 – $89,000
Specifications
Performance
- Engine
- 4.0L V8 M176
- Horsepower
- 496 hp
- Torque
- 516 lb-ft
- Transmission
- 9-Speed Automatic
- Drivetrain
- AWD
Fuel & Efficiency
- Fuel
- Gasoline
- MPG City
- 16 mpg
- MPG Highway
- 24 mpg
- MPG Combined
- 19 mpg
- Fuel Tank
- 22.2 gal
Dimensions
- Length
- 215.3″
- Width
- 75.6″
- Height
- 59.4″
- Wheelbase
- 133.7″
- Curb Weight
- 5,247 lbs
- Cargo Volume
- 12.5 cu ft
Body & Practicality
- Body Style
- Sedan
- Doors
- 4
- Seating
- 5
- Base MSRP
- $184,900
Colors
Factory colors on 2021 Mercedes-Benz S-Class S 580s for sale now.
Exterior
- Black28
- designo Diamond White(white)12
- designo Diamond White Metallic(white)7
- Gray4
- White4
- Cirrus Silver Metallic(silver)3
- Silver3
- Obsidian Black Metallic(black)3
- Graphite Grey(gray)3
- Diamond White(white)3
Interior
- Black36
- Black Nappa Leather(black)5
- Macchiato/Magma Grey(gray)3
- Macchiato(brown)3
- White3
- designo Black(black)2
- Exclusive Sienna Brown/Black(brown)2
- Sienna Brown(black)2
- Brown2
- Red2
Live Market Data
Computed from active 2021 Mercedes-Benz S-Class S 580 listings nationwide, updated continuously.
Price Distribution
Price vs. Mileage
Latest S 580 Listings
The newest 2021 Mercedes-Benz S-Class S 580s on the market.

Used 2021 Mercedes-Benz S-Class
$52,798
Est. $766/mo*
Mercedes-Benz of Fort Myers

Used 2021 Mercedes-Benz S-Class
$54,239
Est. $786/mo*
Sheehy Lexus of Annapolis

Used 2021 Mercedes-Benz S-Class
$59,900
Est. $867/mo*
The Automaster

Used 2021 Mercedes-Benz S-Class
$61,755
Est. $893/mo*
Monti's Auto Center

Used 2021 Mercedes-Benz S-Class
$66,187
Est. $957/mo*
Mercedes-Benz of Los Angeles

Used 2021 Mercedes-Benz S-Class
$47,469
Est. $690/mo*
Mercedes Dealer

Used 2021 Mercedes-Benz S-Class
$67,069
Est. $969/mo*
Mercedes-Benz of Ontario

Used 2021 Mercedes-Benz S-Class
$61,070
Est. $884/mo*
Autohighway, Inc.
What's Yours
Worth?
The median 2021 Mercedes-Benz S-Class S 580 lists for $60,174 today.
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Factory Features
Standard equipment from the window sticker, reviewed for accuracy.
Comfort & Convenience
- KEYLESS-START and KEYLESS-GO keyless entry / push-button start
- Dual-zone automatic climate control with front infrared sensing
- AIR-BALANCE package (ionization and active fragrance)
- Wireless smartphone charging (front)
- HomeLink integrated garage door opener
- Remote engine start (via Mercedes me / smart device)
- Memory settings for driver/passenger seats, mirrors, steering wheel, head restraints, and HVAC
- Power fuel-filler door lock
- Illuminated entry system
- Built-in toll gate transponder
- 6 USB-C ports (4 front, 2 rear) with quick charge and rear 115V power outlet
- Cruise control with steering-wheel controls (supplemented by DISTRONIC)
- Power rear sun blinds (doors and rear window)
Driver Assistance
- Driver Assistance Package (standard): Active Distance Assist DISTRONIC with route-based speed adaptation
- Active Stop-and-Go Assist
- Active Steering Assist with Active Emergency Stop Assist and Active Lane Change Assist
- Active Brake Assist with Cross-Traffic function and turn-off function
- Active Speed Limit Assist with Traffic Sign Assist
- Active Blind Spot Assist with Exit Warning
- Active Lane Keeping Assist
- ATTENTION ASSIST
- Car-to-X Communication
- Active Parking Assist with PARKTRONIC
- 360-degree surround-view camera with 3D View Assist
- Evasion Assist / collision mitigation support
Entertainment
- New-generation MBUX infotainment and navigation with “Hey Mercedes” natural-language voice control
- MBUX Augmented Video for Navigation
- Biometric profile activation (fingerprint sensor; also voice / facial recognition support)
- Wireless Apple CarPlay and Android Auto smartphone integration
- Burmester 3D Surround Sound System with sound personalization (15 speakers; not High-End 4D)
- HD Radio and SiriusXM satellite radio (with trial period)
- Bluetooth wireless connectivity and audio streaming
- Online music streaming / Mercedes me connectivity features
- HERMES LTE mobile hotspot internet access
- Steering-wheel audio and voice controls
Exterior
- LED Intelligent Light System headlamps with Adaptive Highbeam Assist / auto high beams
- LED taillamps and LED daytime running lights
- Panorama sunroof with power sunshades
- KEYLESS-GO seamless flush door handles
- Soft-close doors
- Power-folding heated auto-dimming side mirrors with integrated turn signals
- EASY-PACK power trunk / automatic trunk lid
- HANDS-FREE ACCESS proximity trunk opening
- Powered rear-window sunshade and powered rear door sun blinds
- MAGIC VISION CONTROL heated washer jets / rain-sensing variable intermittent wipers
- Laminated / acoustic glass (heat- and noise-insulating)
- Chrome grille, chrome window trim, and body-colored bumpers with chrome accents
- Perimeter / approach lighting and front LED logo projectors
Interior
- Nappa leather upholstery (standard on S 580 4MATIC)
- 12.3-inch digital instrument cluster
- 12.8-inch OLED touchscreen center display
- New-generation multifunction steering wheel with capacitive touch-control buttons
- Power tilt/telescoping steering column with memory and auto tilt-away
- Leather-wrapped steering wheel
- 64-color Active Ambient Lighting with illuminated door sill panels
- Power front seats with 4-position memory
- Rapid-heating and ventilating Active Multicontour front seats with massage and lumbar support
- Front comfort headrests
- Power windows with one-touch up/down
- Auto-dimming rearview mirror
- Illuminated dual visor vanity mirrors
- Front and rear center armrests with storage
- Carpeted floor mats
- Wood / piano black / metal-look interior accents (design-line dependent)
Mechanical & Performance
- 4.0L twin-turbo V8 Biturbo with EQ Boost 48-volt mild-hybrid system (496 hp @ 5,500 rpm; 516 lb-ft @ 2,000–4,000 rpm; up to ~21 hp / 184 lb-ft EQ Boost assist)
- 9G-TRONIC 9-speed automatic transmission with steering-wheel shift paddles
- 4MATIC full-time all-wheel drive
- ECO start/stop system
- DYNAMIC SELECT drive modes
- AIRMATIC air suspension with Adaptive Damping System (ADS+) — multi-link front and rear, automatic height adjustment
- Speed-sensitive electromechanical power steering
- 4-wheel ventilated disc brakes with ABS, Brake Assist, hill-start assist, and electric parking brake
- Electronic Stability Program (ESP) with Crosswind Assist and traction control
- Brake-actuated limited-slip differential
- 19-inch alloy wheels with 255/45R19 tires
- Electronically limited top speed 130 mph; ~4.4 sec 0–60 mph (factory)
Safety & Security
- Dual-stage front airbags; front side airbags; driver knee airbag; side curtain airbags
- Rear side-impact airbags
- PRE-SAFE system including PRE-SAFE PLUS (rear collision prep) and PRE-SAFE Sound
- PRE-SAFE Impulse Side
- Electronic Stability Program (ESP) and ABS with Brake Assist
- Tire-pressure monitoring system
- Anti-theft alarm system with engine immobilizer
- eCall / Mercedes-Benz emergency SOS capability
- Child-seat sensors / LATCH anchors and rear child safety locks
- 3-point seat belts with pretensioners and height adjusters
Warranty
- New Vehicle Limited Warranty: 4 years / 50,000 miles (bumper-to-bumper)
- Powertrain coverage: 4 years / 50,000 miles
- Corrosion perforation: 4 years / 50,000 miles
- Mercedes-Benz Roadside Assistance: 4 years / 50,000 miles