2022 Lexus RX 350 Premium

The 2022 RX 350 is a midsize luxury SUV that anchors Lexus's lineup with a reputation for comfort and quiet refinement. It competes with the Acura MDX, BMW X5, and Mercedes-Benz GLE, though it leans more toward plush cruising than sporty handling. The V6 delivers smooth, effortless acceleration, and the cabin stays hushed at highway speeds. The ride is supple and absorbs bumps well, though the F Sport trims firm things up for sharper handling. The RX offers a roomy five-passenger cabin, generous cargo space, and a power liftgate on most trims. The Premium trim is the one to pick if you want genuine leather upholstery and a power liftgate without stepping up to the Luxury. The 3.5L V6 makes 290 horsepower and pairs with a eight-speed automatic, all driving through all-wheel drive for planted all-weather traction; expect 22 mpg combined on average.