2010 Lexus RX 350 350

This is Lexus's midsize luxury SUV, the one that made the segment famous for quiet comfort rather than sporty moves. The RX drives with a smooth, unhurried character that suits its mission, though it's not the last word in agility. The ride is genuinely plush, and the cabin stays whisper-quiet even at highway speeds, which is exactly what buyers want here. You get a spacious five-seat cabin with a useful cargo area, and the rear seats fold nearly flat for bulky loads. The 3.5L V6 makes 275 horsepower and pairs with a six-speed automatic that shifts gently, delivering 20 mpg combined in mixed driving. The optional adaptive cruise and pre-collision system were rare for the segment in 2010, and they work seamlessly with the RX's relaxed character.